Streep is joined by British favourite Jim Broadbent as ever-loyal husband Denis Thatcher with Alexandra Roach and Harry Lloyd playing the younger version of the pair.
The film is a Pathé, Film4, UK Film Council presentation with the participation of Canal+ and Cine Cinema in association with Goldcrest Film Production LLP of a DJ Films Production.
Written by award-winning writer Abi Morgan (Sex Traffic, Brick Lane, White Girl), directed by Phyllida Lloyd CBE (Mamma Mia) and produced by Damian Jones (The History Boys, Adulthood), the film will be executive produced by Francois Ivernel and Cameron McCracken for Pathé, by Tessa Ross for Film4 and by Adam Kulick for Goldcrest.